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Purdue School of Engineering and Technology

Purdue School of Engineering and Technology

Imaging-Based Computational Analysis of Biomedical Flows

ME 59700 / 3 Cr. (3 Class)

This course consists of three parts: (1) concepts and principles of hemodynamic flows including anatomy of cardiovascular system, cardiovascular physiology, flow modeling and features, governing equations; (2) cardiovascular imaging and geometry modeling; (3) patient-specific computational hemodynamics and related medical diagnose and assessment of cardiovascular diseases. Team projects to evaluate hemodynamics in human arteries based on CT/MRI images will provide the first-hand experience of how engineering analysis can contribute to medical innovation and advance.   

Textbooks

M. Thiriet, Biology and Mechanics of Blood Flows Part II: Mechanics and Medical Aspects, Springer. P. Galdi, R. Rannacher, A. M. Robertson, and S. Turek, Hemodynamical Flows ¾ Modeling, analysis, and Simulation, Birkhauser Verlag, AG, 2000 B. C. Lopez and E. Pena (eds), Patient-specific Computational Modeling, Springer Note: these books can be downloaded from IUCAT

Outcomes

Upon completion of the course, students are expected to be able to do the followings

1. To have a sound background in the physiological insight of hemodynamic flows

2. To be able to understand hemodynamic assessment in modern clinical practice for major cardiovascular diseases

3.  To be able to understand governing equations for blood flows from Navier-Stokes equations and apply them to different medical flow scenarios

4. To be able to extract anatomical arteries/vessels from CT/MRI angiographies.

5. To be able to noninvasively evaluate hemodynamics including velocity, pressure, wall shear stress, etc. for individual patient

Topics
  • Anatomy of cardiovascular systems
  • Physiology of cardiovascular systems
  • Cardiac Imaging
  • Rheology
  • Hemodynamics
  • Numerical Simulations
  • Patient-specifc computation hemodynamics