Purdue School of Engineering and Technology

Purdue School of Engineering and Technology

Joseph Wallace

  • Associate Professor of Biomedical Engineering
Joseph Wallace

SL 220D
Professional Website


  • The University of Michigan, Biomedical Engineering, Ph.D., 2007

Professional Experience

  • Postdoctoral Fellow, The University of Michigan, Department of Chemistry and Michigan Nanotechnology Institute for Medicine and Biological Sciences, 10/2007 - 9/2010
  • Graduate Research Assistant, The University of Michigan, Biomimetics and Biomechanics of Hard Tissues Laboratory, Department of Biomedical Engineering , 5/2002 - 10/2007

Selected Publications

  • Newman CL, Tian N, Hammond MA, Wallace JM, Brown DM, Chen NX, Moe SM, Allen MR, “Clinically relevant suppression of hyperparathyroidism with calcitriol does not improve skeletal properties in an animal model of chronic kidney disease,” American Journal of Nephrology, 2016, In Press., 2/2016
  • Newman CL, Creecy A, Granke M, Nyman JS, Tian N, Hammond MA, Wallace JM, Brown D, Chen N, Moe SM, Allen MR, “Raloxifene improves skeletal properties in an animal model of chronic kidney disease,” Kidney International, 2016; 89: 95-104., 1/2016
  • Meneghini RM, Lovro LR, Wallace JM, Ziemba-Davis, M, “Large Metal Heads and Vitamin-E Polyethylene Increase Frictional Torque in Total Hip Arthroplasty,” In Press, The Journal of Arthroplasty, 2015, doi:10.1016/j.arth.2015.09.020., 1/2016
  • Abeysekera I, Thomas, J, Georgiadis TM, Berman AG, Hammond MA, Dria KJ, Wallace JM, Roper RJ, “Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model,” Molecular Nutrition and Food Research, 2015, In Press, DOI: 10.1002/mnfr.201500781., 1/2016
  • Berman AG, Wallace JM, Bart ZB, Allen MR, “Raloxifene reduces skeletal fractures in an animal model of osteogenesis imperfecta”, Matrix Biology, 2015, In Press, doi:10.1016/j.matbio.2015.12.008., 1/2016
  • Wallace JM “Effects of fixation and demineralization on bone collagen D-spacing as analyzed by atomic force microscopy,” Connective Tissue Research, 2015; 56(2): 68-75., 1/2015
  • Hammond MA, Wallace JM, "Exercise prevents Beta-aminopropionitrile induced morphological changes to Type I collagen in Murine Bone," BoneKEy Reports, 2015; 4(645): 1-5., 1/2015
  • Wallace JM, Bone HG, Invited Commentary, “Effects of Estrogen Depletion and Drug Treatment on Collagen Microstructure: Implications,” BoneKEy Reports, 2015; 4(698): 1-2., 1/2015
  • Srisuwananukorn A, Allen MR, Brown DM, Wallace JM, Organ JM, "In vivo reference point indentation measurement variability in skeletally mature inbred mice," BoneKEy Reports, 2015; 4(712): 1-5., 1/2015
  • Berman AG, Clauser CA, Wunderlin C, Hammond MA, Wallace JM, “Cortical and Cancellous Structural Adaptation and Improvements to Mechanical Integrity are Strain Dependent with Axial Compression of the Tibia in Female C57BL/6 Mice,” PloS One, 2015; 10(6): e0130504., 1/2015
  • Hammond MA, Gallant MA, Burr DB, Wallace JM, “Nanoscale Changes in Collagen are Reflected in Physical and Mechanical Properties of Bone at the Microscale in Diabetic Rats,” Bone, 2014; 60: 26-32., 1/2014
  • Diaz Gonzalez A, Gallant MA, Burr DB, Wallace JM, "Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes," Journal of Biomechanics, 2014; 47(3): 681-686., 1/2014
  • Shin JW, Dodge TR, Hammond MA, Wallace JM, Yokota H, "Physical weight loading induces expression of tryptophan hydroxylase 2 in brain stem," PLoS One, 2014; 9(1): e85095., 1/2014
  • Gallant MA, Brown DM, Hammond M, Wallace JM, Du J, Deymier-Black A, Stock SR, Allen MR, Burr DB, “Bone cell-independent benefits of raloxifene on the skeleton: A novel mechanism for improving bone material properties,” Bone, 2014; 61:191-200., 1/2014
  • Newman CL, Moe SM, Chen NX, Hammond MA, Wallace JM, Nyman JS, Allen MR, “Cortical bone mechanical properties are altered in an animal model of progressive chronic kidney disease,” PLoS One, 2014; 9(6): e99262., 1/2014
  • Bart ZR, Hammond MA, Wallace JM, "Multi-scale Analysis of Bone Chemistry, Morphology and Mechanics in the oim Model of Osteogenesis Imperfecta," Connective Tissue Research, 2014; 55(S1): 4-8., 1/2014
  • Wallace JM “Comment on “The ultrastructure of type I collagen at nanoscale: large or small D-spacing distribution?” by H.-N. Su, L.-Y. Ran, Z.-H. Chen, Q.-L. Qin, M. Shi, X.-Y. Song, X.-L. Chen, Y.-Z. Zhang and B.-B. Xie, Nanoscale, 2014, 6, 8134” Nanoscale, 2015; 7(3):1233-1234., 1/2014

Awards, Honors, and Certifications

  • New Investigator Award, Eleventh International Conference on the Chemistry and Biology of Mineralized Tissues, 10/2013
  • 2013 Summer Research Grant from The Purdue Research Fund, “Effects of in vivo & ex vivo tibial compression on bone damage accrual and fracture toughness”, 5/2013
  • Finalist - New Investigator Research Award, The 57th Annual Meeting of the Orthopaedic Research Society , 1/2011


Mechanical Properties of Biological Tissues, Mechanically-mediated skeletal adaptation, Atomic Force Microscopy


Bone Biology and Mechanics, Hierarchical structure/function relationships in cells, tissues and organs, Mechanical Loading Models, Collagen, Bone disease